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山楂叶总黄酮活血化瘀作用实验研究 被引量:29

Experimental Research of Blood-quickening Stasis-transforming Actions of Hawthorn Leaf Flavonoids
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摘要 目的:观察山楂叶总黄酮(Hawthorn Leaves Flavonoids,HLF)活血化瘀作用。方法:采用体内血栓形成、血小板聚集、微循环、血液流变学测定等方法。结果:HLF可显著抑制大鼠血栓形成,抑制ADP诱导的小鼠血小板体外聚集,显著改善小鼠耳廓微循环状态,降低大鼠血液粘度。结论:HLF具有良好的活血化瘀作用。 Objective: To investigate the blood - quickening stasis - transforming actions of hawthorn leaf flavonoids in different circles. Method: The methods of formation of thrombin in vivo , aggregation of platelets and microcirculation were used . Result: Hawthorn leaf flavonoids could obviously inhibit formation of thrombin , inhibit platelet aggregation induced by ADP , improve the microcirculation blood - quickening and stasis- transforming actions significantly. Conclusion: Hawthorn leaf flavonoids possesses obvious ac- tions of blood - quickening and stasis - transforming.
出处 《河北医学》 CAS 2009年第1期22-23,共2页 Hebei Medicine
关键词 山楂叶总黄酮 血栓 血小板聚集 微循环 Hawthorn leaf flavonoids Thrombin Platelet aggregation Microcirculation
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  • 1Giovamni Diminno, Melvin J, Silver. Mouse antithromobotic assay:A simple method for the evaluation of antithromobotic agents in vivo. potentiation of antithromobotic activity by ethyl alohol [ J ]. The Journal of Pharmacology and Experiment Therapeutics, 1983,225 ( 1 ) :57.
  • 2陈奇.中药药理研究方法[M].北京:人民卫生出版社,1993.636.

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