摘要
风疹病毒是披膜病毒科风疹病毒属的惟一成员,是第一个被证明具有致畸性的病毒。如果在妊娠的前3个月感染了风疹病毒,具有很高的先天性风疹综合症(CRS)的风险,特别是那些没有免疫保护的妇女。应用先进的产前诊断技术鉴别鉴别诊断胎儿有无损伤是非常必要的,因为当在妊娠前3个月被诊断为原发性风疹病毒感染,孕妇要考虑是否妊娠终止。在这篇文章里我们主要综述了风疹病毒(RV)的流行病学、基因结果、临床特征和RV的实验室诊断。
Rubella virus （RV） is the only member of the genus Rubivirus in the family of Togaviridae; Rubella is the first virus demonstrated as a teratogen. There is a high risk to develop congenital rubella syndrome （CRS） if the infection occurs in the first trimester of pregnancy, particularly in women without specific immunological protection. Specific therapies to prevent CRS are not available. Advanced prenatal diagnostic techniques should be offered to the women especially in order to distinguish the cases without fetal damage as termination of pregnancy is considered when primary rubella is diagnosed during the first trimester. In this review we focus on the epidemiology, the gene structure, the clinic feature and the laboratory diagnosis of RV.
出处
《安徽卫生职业技术学院学报》
2008年第6期72-74,共3页
Journal of Anhui Health Vocational & Technical College
