摘要
目的:观察中药合剂AA-3对胰腺的保护作用。方法:健康SD大鼠随机分成3组,假手术组、模型组、中药治疗组。Aho’法复制急性重症胰腺炎。建立荧光显微流速测试系统,观察造模后24小时胰腺微血管血流的变化,检测血清、腹水淀粉酶,并观察胰腺病理组织学改变及超微结构改变。结果:模型组同一只大鼠的胰腺微动、静脉存在着不同的血流速度,治疗组血流速度则相对一致。模型组胰腺组织结构损害明显,而中药治疗组损害明显改善。结论:中药合剂AA-3能明显改善SAP大鼠胰腺结构和功能。
Objective:To observe the protective effects of Chinese medicine mixture AA-3 on pancreatic structure and function of sever acute pancreatitis.Methods:SD rats were randomly divided into three groups,sham group,model and Chinese medicine AA-3 groups.Sever acute pancreatitis models were copied by Aho's method.Fluorescent microscope speed test system was established to observe the microvascular changes of pancreas after modeling 24h,serum and ascites amylase,pathological changes of the pancreas and its ultrastructure were determined.Results:There was different blood flow rate in the pancreas microcirculation arteries and veins in the same rat with sever acute pancreatitis,the blood flow rate in the pancreas microcirculation arteries and veins was uniforms in AA-3 group rats.Pancreatic structure was damaged obviuosly in sever acute pancreatitis rats,the damage was significantly improved in AA-3 group.Conclusion:Chinese medicine mixture AA-3 can obviuosly protect pancreatic structure and function of rats with sever acute pancreatitis.
出处
《中国中医药科技》
CAS
2008年第6期410-412,共3页
Chinese Journal of Traditional Medical Science and Technology
