摘要
目的探讨CT导向下^125I粒子植入治疗技术在结直肠癌肝转移瘤治疗中的意义。方法2006年7月至2007年8月对15例结直肠癌肝转移患者采用CT引导下^125I放射性粒子植入，粒子植入前采用治疗计划系统（treatment planning system，TPS）模拟布源或遵循Halarism的^125I经验公式（mCi=Da×5），计算术中所需^125I粒子的总活度及治疗粒子的数量。在螺旋CT导向下将^125I放射性粒子植入肝转移瘤实质内及肿瘤边缘。结果治疗3个月后行肿瘤影像学评价，15例患者中完全缓解（complete remission，CR）2例，部分缓解（partial remission，PR）10例，稳定（nochange，NC）3例。随访至今全组15例全部存活，随访时间最长20个月，最短6个月，近期平均生存期12个月。结论CT导向下^125I粒子植入是治疗直肠癌肝转移瘤的安全、微创、有效的方法。
Objective To evaluate CT guided ^125I seeds implantation for liver metastasis of colorectal cancer. Methods The retrospective analysis was undertaken in 15 eoloreetal cancer patients with 33 loci of hepatic metastases from Jul 2006 to Aug 2007, receiving CT guided ^125I radioactive seeds implantation according to TPS or Halarism＇s experience function ： mCi = Da × 5, Results All the patients were followed-up by CT scan after 3 months. There were 2 of complete remission （ CR ） ,10 of partial remission （PR）, 3 of stable disease （SD）. All patients are still alive now, the longest follow-up time is 20 months, and the shortest is 6 months, the average followed span is 12 months. Conclusion CT guided ^125I seeds implantation is a safe and effective method in the treatment of liver metastasis caused by colorectal cancer.
出处
《中华普通外科杂志》
CSCD
北大核心
2008年第11期877-880,共4页
Chinese Journal of General Surgery
