摘要
目的:研究头皮脂溢搽剂的制备工艺。方法:采用正交试验设计L9(34),以60%乙醇为溶剂,以盐酸小檗碱含量为考察指标,以提取方法、提取时间、溶剂用量和提取次数为考察因素,确定最佳制备工艺。结果:最佳制备工艺为采用浸渍法,提取时间为48h,60%乙醇用量1500mL,提取次数为2次。结论:本工艺稳定、可行,可为头皮脂溢搽剂的工业化生产提供理论依据。
OBJECTIVE： To study the preparation technology of Chinese traditional medicine Seborrhea liniment. METHODS： The preparation technology of Seborrhea liniment was optimized by orthogonal experiment design L,（34） using 60% alcohol as solvent with the content of Berberine hydrochloride as index for evaluation and with the extraction method, extraction time, amount of solvent and number of extraction times as factors. RESULTS： The optimum preparation technical conditions were as follows： by impregnating method, the extraction time was 48 h using 1 500 mL alcohol and the extraction frequency was 2 times.CONCLUSION ：The preparation technology of Chinese traditional medicine Seborrhea liniment is stable and feasible, and it serves as a theoretical basis for the industrial production.
出处
《中国药房》
CAS
CSCD
北大核心
2008年第33期2580-2581,共2页
China Pharmacy
关键词
头皮脂溢搽剂
制备工艺
正交试验
盐酸小檗碱
Seborrhea liniment
Preparation technology
Orthogonal experiment
Berberine hydrochloride
