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乏氧与肿瘤干细胞的放射敏感性 被引量：1

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摘要 随着对肿瘤生物学特性的深入研究，目前认为一些恶性实体肿瘤是一种干细胞疾病，如脑胶质瘤、乳腺癌和大肠癌等，即肿瘤来源于肿瘤干细胞（cancer stem cell），又称为肿瘤起始细胞（cancer-initiating cell）。这类细胞仅占整个肿瘤细胞的一小部分，但是它们具有自我更新能力和多向分化潜能，是形成不同分化程度的肿瘤和肿瘤不断生长的根源，也可能是肿瘤治疗失败的根源。
作者 陆雪官 田野
机构地区 苏州大学附属第二医院肿瘤放疗科
出处 《中华放射肿瘤学杂志》 CSCD 北大核心 2008年第6期487-488,共2页 Chinese Journal of Radiation Oncology
基金 苏州大学医学发展基金重点项目（EE123706）
关键词 肿瘤干细胞 放射敏感性 肿瘤生物学特性 乏氧 恶性实体肿瘤 多向分化潜能 自我更新能力 细胞疾病
分类号 R686 [医药卫生—骨科学]
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共引文献125

同被引文献10

  • 1陆雪官,冯炎.检测肿瘤细胞乏氧的生物学指标的研究进展[J].中华放射肿瘤学杂志,2005,14(3):236-238. 被引量：8
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中华放射肿瘤学杂志
2008年 第6期

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