摘要
本研究应用多普勒组织显像技术以正常人检测结果为基础,评价心绞痛、急性和陈旧性心肌梗塞病人的心肌缺血和梗塞的部位及程度。同时将其应用于多巴酚丁胺药物负荷试验。以上评价结果均与ECT^(99m)Tc心肌血流灌注显像结果进行比较。结果发现:多普勒组织显像显示缺血和硬塞部位心肌存在与正常心肌不同的异常速度和加速度分布,此分布有明显边界。多普勒组织显像在较低药物负荷剂量下显示了轻微的室壁异常运动及其变化。多普勒组织显像所示心肌缺血和梗塞部位与ECT检测心肌缺血和梗塞部位的吻合率分别为67%和80%;辅助多巴酚丁胺药物负荷试验所示心肌缺血和梗塞部位与后者的吻合率为86%。结果表明:多普勒组织显像能够较为准确、直观地反映心肌缺血和梗塞的部位和程度,从而提高了超声心动图评价冠心病的准确性和效率。进一步控制多普勒组织显像的影响因素是提高诊断质量的关键。
The normal cases(n=30)and the patients suffering from angina(n=20), acute(n=19).and old (n=54) myocardium infarction underwent the examination of Doppler Tissue Imaging(DTI). At the same time, the DTI techniques was applied in Dobatumin Srtess Examination (DSE)(n=13). The results including position and extent of ischemia and infarction in these studies were compared with the results of myocardial perfusion imaging of SPECT. The results showed that there were various abnormal velocity and acceleration distribution differed from normal myocardium of ventricular wall covered the positions of ischemia and infarction with a define margin. DTI present the mild abnormal segment motion of ventricular wall and its changes with, a lower dose in DSE. The rates of position conformation between DTI and SPECT of ischemia and infarction were 67% and 80% seperately. The rate of positionconformation between DTI and SPECT of ischemia and infarction in DSE was 86%. The results indicated that DTI can present the position and extent of ischemia and infarction more directely and accurately, and bring a higher efficiency to echocardiograhy in evaluating coronary artery heart diseases. The further control of influence factors is the key to improve the quality of DTI diagnosis.
关键词
多普勒组织显像
冠心病
诊断
Doppler tissue imaging Coronary artery diseases
