摘要
目的:观察自拟活血降脂汤治疗高脂血症的临床疗效。方法:将100例高脂血症患者随机分为对照组与治疗组,治疗组60例应用活血降脂汤,对照组40例以血脂康胶囊治疗。两组患者治疗12w后观察临床疗效、血脂[总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)]、载脂蛋白(ApoA-I、ApoB)及安全性指标。结果:两组患者治疗后,治疗组总有效率为90.0%,对照组为85.0%;两组总有效率比较,无显著性差异(P>0.05)。在降低TG、ApoB和升高ApoA-Ⅰ方面治疗组优于对照组,两组比较有显著性差异(P<0.05,P<0.01)。两组中医证候疗效及治疗前后症状积分比较,有显著性差异(P<0.01)。结论:活血降脂汤能明显改善血脂代谢,是一种疗效确切、应用安全的降血脂汤剂。
Objective：To observe the clinical therapeutic effect of self-prescribed decoction of activating blood circulation and reducing lipid on hyperlipemia. Methods： 100 cases of hyperlipemia were randomized into control group and treatment group. In treatment group（60 cases）, decoction of activating blood circulation and reducing lipid was administrated,in control group （40 cases）,Xne Zhi Kang Capsule （capsule for blood lipid reducing）was administrated. After treated for 12 weeks, the clinical therapeutic effect, blood lipid level （TC, TG, LDL-C, HDL-C）, apolipoprotein （Apo A-I, Apo B） and safety index were observed in two groups. Results：After treatment, the total effective rate was 90.0% in treatment group and was 85.0% in control group,indicating non-significant difference in comparison （P〈0.05）. The outcomes of reducing TC, Apor B and increasing Apo A-I in treatment group were superior to those in control group, presenting significant difference （P〈0.05,P〈0.01）. The comparison of symptomatic therapeutic effect and symptom integrals presented significant difference before and after treatment in two groups（P〈0.01）. Conclusion：Decoction of activating blood circulation and reducing lipid improves blood lipid metabolism remarkably and presents definite therapeutic effect and safety in application.
出处
《世界中西医结合杂志》
2008年第8期471-473,共3页
World Journal of Integrated Traditional and Western Medicine
关键词
高脂血症
活血降脂汤
血脂康胶囊
血脂
痰瘀阻滞证
Hyperlipemia
decoction of activating blood circulation and reducing lipid
Xue Zhi Kang Capsule
retention of phlegm and stasis
