1Peltomaki P. Deficient DNA mismatch repair: a common etiologic factor for colon cancer [ J ]. Human Molecular Genetics, 2001,10 ( 7 ) :735 - 740.
2Jass JR. Hereditary non. polyposis polorectal cancer: the rise and fall of a confusing term [ J ]. World J Gastroenterol. 2006,12(31 ) :4943 -4950.
3Zhang J, Lindroos A, Ollila S,et al. Gene conversion is a frequent mechanism of inactivation of the wild - type allele in cancers from MLH1/MSH2 deletion carriers[ J]. Cancer Research,2006,66(2) :659 -664.
4Raptis S, Mrkonjic M, Green RC , et al. MLH1 -93G > A promoter polymorphism and the risk of microsatellite - unstable colorectal cancer. Journal of the National Cancer Institute,2007,99(6) :463 - 474.
5Blasi MF, Ventura I, Aquilina G, et al. A human cell - based assay to evaluate the effects of alterations in the MLH1 mismatch repair gene [ J ]. Cancer Research,2006, 66(18) :9036 -9044.
6Zecevic M, Amos CI, Gu X J, et al. IGF1 gene polymorphism and risk for hereditary nonpolyposis colorectal cancer [ J ]. Journal of the National Cancer Institute ,2006, 98(2) :139 - 143.
8Goecke T, Schulmann K, Engel C, et al. Genotype - phenotype comparison of german MLH1 and MSH2 mutation carriers clinically affected with lynch syndrome:a report by the german HNPCC consortium[J]. Journal of Clinical Oncology,2006,24(26) :4 285 - 4 292.
10Lynch HT, Coronel SM, Okimoto R, et al. A founder mutation of the MSH2 gene and hereditary nonpolyposis colorectal cancer in the united states [ J ]. JAMA, 2004, 291 (4) :718 -724.
5Lynch HT,Shaw MW,Magnuson CW,et al.Hereditary factors in cancer[J].Arch Intern Med,1966,117:206-212.
6Vasen HFA,Mecklin JP,Khan PM,et al.The international collaborative group on hereditary non-polyposis colorectal cancer(ICG-HNPCC)[J].Dis Colon Rectum,1991,34:424-425.
7Vasen HFA,Watson P,Mecklin JP,et al.New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC,Lynch syndrome)proposed by the International Collaborative Group on HNPCC[J].Gastroenterology,1999,116:1453-1456.
8Rodriguez-Bigas MA,Boland CR,Hamilton SR,et al.A national cancer institute workshop on hereditary nonpolyposis colorectal cancer syndrome:meeting highlights and bethesda guidelines[J].Journal of the National Cancer Institute,1997,89:1758-1762.
9Umar A,Boland CR,Terdiman JP,et al.Revised Bethesda guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome)and microsatellite instability[J].J Natl Cancer Inst,2004,96(4):261-268.
10Pino MS,Chung DC.Application of molecular diagnostics for the detection of Lynch syndrome[J].Expert Rev Mol Diagn,2010,10(5):651-665.