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柴胡合剂抗肝纤维化作用的初步临床研究 被引量:4

Clinical Study of the Treatment of Liver Fibrosis with Compound Bupleurum Mixture
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摘要 观察柴胡合剂抗肝纤维化作用。选择慢性活动性肝炎、早期肝硬化病人20例,柴胡合剂9g/次,每日3次口服,服药时间平均(8±3)个月。初步临床观察发现,柴胡合剂具有降低患者血清转氨酶及提高白蛋白水平的作用,同时能明显降低血清透明质酸及血清Ⅲ型前胶原水平,使肿大的肝脾回缩趋于正常,初步表明柴胡合剂有良好的改善肝功能及抗肝纤维化作用。 The effects of compound Bupleurum mixture (CBM) were investigated on liver fibrosix of 20 cases with chronic active hepatitis or early cirrhosis. CBM were given orally,the dosage was 9g× 3 per day for 6~12 months mean (8± 3)months. The results were as follows;all patients liver function improved significantly than before treatment (P<0. 05). The levels of serum procollagen Ⅲ type (PCⅢ) and hyaluronic acid(HA)were -significantly lower than before treatment(P<0. 05). These results suggested that CBM could improve liver function and inhibit the formation of fibrosis in early liver cirrhosis and chronic active hepatitis.
出处 《天津医药》 CAS 1997年第11期665-666,共2页 Tianjin Medical Journal
关键词 柴胡合剂 抗肝纤维化 肝硬化 中医药疗法 Bupleurum liver function hyaluronic acid PCⅢ early liver cirrhosis chronic active hepatitis
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  • 1殷蔚荑,王宝恩,马晓丽,常德成,黄德庄,范大炽.血清Ⅲ型前胶元肽测定在肝纤维化诊断中的意义[J]临床肝胆病杂志,1986(03).

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