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内科合并疾病及患者特征与乳腺癌术后皮下积液关系的临床研究 被引量:12

Relationship between seroma formation after operation of breast cancer with comorbidity of internal diseases and patients' characteristics:a clinical study
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摘要 目的:探讨乳腺癌手术患者内科合并疾病与术后皮下积液发生的关系。方法:收集130例乳腺癌患者的相关临床资料,前瞻性观察其是否发生积液,单因素分析和多因素分析比较积液组与对照组在积液发生危险因素上的差异。结果:单因素分析显示积液组平均年龄大(59.13岁vs51.37岁,P=0.002),体质量指数(body mass index,BMI)大(25.33vs22.90,P=0.018),合并高血压者多(30.4%vs12.1%,P=0.027)。Logistic回归分析显示年龄(OR=1.065,95%CI=1.012~1.116,P=0.016)、BMI(OR=1.193,95%CI=1.025~1.389,P=0.023)是皮下积液发生的独立危险因素。结论:乳腺癌术后皮下积液的发生与年龄、BMI、合并内科疾病有关,注重围术期的调整处理可能有助于减少皮下积液的发生。 Objective:To investigate the relationship between the incidence of postoperative seroma formation and the comorbidity of internal diseases. Methods.Clinical data from 130 patients who underwent breast surgery in the department of breast cancer in our hospital were collected and the seroma formation was observed prospectively. Univariate and muhivariate analyses were used to analyze the risk factors related with seroma formation. The difference was compared between the seroma formation group and the control group. Results: Univariate analysis showed that the average of age ( 59. 13 years old vs 51.37 years old, P = 0. 002 ) and body mass index (BMI) (25.33 vs 22.90, P =0.018) were both significantly higher in the seroma formation group. The incidence of hypertension was higher in the seroma group (30.4% vs 12. 1% , P = 0. 027 ). Logistic regression analysis showed that age ( OR = 1. 065, 95% CI = 1.012-1.116, P = 0.016 )and BMI ( OR = 1.193, 95 % CI = 1. 025-1. 389, P = 0.023 ) were independent risk factors for seroma formation. Conclusion:The incidence of postoperative seroma formation after breast surgery was related with age, BMI and comorbidity of internal diseases. The appropriate management during perioperative period may be beneficial for decreasing the incidence of seroma formation.
出处 《肿瘤》 CAS CSCD 北大核心 2008年第7期601-604,共4页 Tumor
关键词 乳腺肿瘤 手术后并发症 血清肿 Breast neoplasms Postoperative complications Seroma
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