摘要
目的了解铜绿假单胞菌(PA)的感染分布及其耐药状况,为临床治疗提供依据。方法采用回顾性的方法,统计分析441株PA的标本来源、感染科室分布及耐药状况。结果441株PA有357株来自痰液,占80.95%,分离PA的科室分别为重症监护病房(ICU)占26.53%、呼吸科占20.63%、神经外科占19.05%、老年内科占17.01%。药敏结果显示,铜绿假单胞菌最敏感的抗生素是美罗培南(总耐药率为13.61%),抗菌作用最差的是氨苄西林/舒巴坦(总耐药率为91.38%)。铜绿假单胞菌对常用抗生素耐药性的变化呈上升的趋势。结论铜绿假单胞菌临床分离株多来自痰液和ICU病房,并对多种抗菌药物的耐药率较高,多重耐药性明显。
Objective To investigate the distribution and drug resistance state of Pseudomonas aeruginosa, so as to offer reasonable experimental data for clinical therapy. Methods A statistic analy- sis for the specimen source, distribution of infected departments and drug resistance state to 441 isolates was conducted in a retrospective way. Results Among 441 strains, 357 （80.95%） were isolated from sputum species. The department with the highest isolating rate was ICU （26.5%）, followed by department of respiratory disease （20.63 % ）, department of neurosurgery （19.05 %） and department of geriatrics （17.01%）. The most sensitive antibiotic was Meropenem, which total drug resistance rate was 13.61 % ; the most insensitive antibiotic was ampicillin-sulbactam, which total drug resistance rate was 91.38%. The drug resistance rate of P. aeruginosa was increasing year by year. Conclusion Clinical isolates of P. aeruginosa mostly come from sputum samples and ICU, and they are highly and multidrug resistant to various antibiotics.
出处
《国际检验医学杂志》
CAS
2008年第7期592-594,共3页
International Journal of Laboratory Medicine
关键词
假单胞菌
铜绿
交叉感染
抗药性
细菌
抗菌药
Pseudomonas Aeruginosa
Cross infection
Drug resistance,Bacterial
Anti Bacterial Agents
