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多西紫杉醇联合顺铂治疗晚期食道癌的疗效观察

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摘要 目的探讨多西紫杉醇联合顺铂治疗晚期食道癌的疗效及毒副反应。方法入组26例病理诊断的食道癌应用多西紫杉醇联合顺铂方案(多西紫杉醇60mg第1、8天+顺铂40mg第2~4天)化疗2个周期以上评价疗效。结果CR1例,PR14例,NC6例,PD5例,临床有效率(CR+PR)57.7%。主要不良反应是可逆性的骨髓抑制和胃肠反应,Ⅲ、Ⅳ度少见,未见明显肝肾毒性。结论多西紫杉醇联合顺铂治疗国人晚期食道癌疗效和安全性均较好,毒性反应可以耐受,值得进一步研究和观察。
出处 《中国实用医药》 2008年第19期F0003-F0003,共1页 China Practical Medicine
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