摘要
目的研究老年人血压控制状况对颅内动脉血流动力学的影响。方法高血压组132例,为常规体格检查排除高血脂、高血糖的老年高血压患者,对照组80例,为同期体检无高血压、高血糖、高血脂及心脑血管病史者;根据血压控制效果,再将高血压组分为正规治疗组(80例)和非正规治疗组(52例)。采用经颅多普勒超声(TCD)检测颅内动脉血流动力学的变化,比较各组频谱形态异常检出率,及各组颅内动脉收缩峰流速异常率有无差异。结果高血压组与对照组比较,血流频谱异常率明显增高(P<0.01),正规治疗组与非正规治疗组血流频谱异常率差异不明显(P>0.05)。各组颅内动脉收缩峰流速均有差异,高血压组异常率明显高于对照组(P<0.01),非正规治疗组异常率高于正规治疗组,差异有统计学意义(P<0.05)。结论血压状况对老年人脑血流动力学有明显影响,高血压患者进行正规治疗对预防老年人脑血管病发生具有重要意义。
Objective To study the effect of controlling blood pressure on brain hemodynamics in aged patients. Methods The hypertension group （group H） had 132 aged patients, who were diagnosed as hypertension （hyperglycosemia and hyperlipidemia were excluded） by routine examines. While the control group （group C） had 80 aged patients, who were diagnosed as neither hypertension nor hyperglycosemia or hyperlipidemia. According to blood pressure controlling, patients in group H were subdivided into treated group （group T, n=80）, with normal anti - hypertension treatment, and none-treated group （group N, n = 52）, without normal treatment. Transcranial Doppler（TCD） was used to identify intracranial hemodynamic change and character of blood wave. The rates of abnormal spectrum and abnormal intracranial arterial systolic peek speed were compared among the groups. Results Considering the rate of abnormal blood flow spectrum, which in group H was obviously higher than that in group C （P〈0.01） However, there was no difference between group T and group N （P〉0.05）. Whereas concerning the intracranial arterial systolic peek speed, there was significant difference among the groups, which in group H was higher than that in group C （P〈0.01）, while that in group N was higher than that in group T （P〈0.01）. Conclusion Controlling of blood pressure has an obvious effect on hemodynamic status in the aged patients. Furthermore, normal anti- hypertension treatment is of great importance in prevention of brain vessel diseases in aged patients.
出处
《中国煤炭工业医学杂志》
2008年第8期1150-1151,共2页
Chinese Journal of Coal Industry Medicine
