摘要
目的通过对以主动脉夹层（AD）首诊为阻塞性睡眠呼吸暂停综合征（OSAHS）患者的临床资料分析，总结其临床特点，提高诊断意识。方法回顾性分析6例OSAHS合并AD患者的临床资料，结合文献复习，探讨OSAHS对AD的影响。结果6例AD首诊的OSAHS患者均为肥胖男性，体质指数（BMI）平均32．72±3．57；平均年龄（43、83±2．14）岁；有不同程度的夜间憋醒和白天嗜睡，ESS嗜睡评分平均（13．83±2．14）分；睡眠呼吸暂停低通气指数（AHI）≥62：L／h，平均（73．35±9．16）：L／h，均为重度OSAHS；最低脉搏容积血氧饱和度（LSp02％）为（58．67±10．95）％，氧减〈90％的时间（min）[T90（min）]平均（244．20±144、74）min，血氧饱和度〈90％的时间占总监测时间的百分比（TS90％）平均为（54.48±30．18）％。均伴有2年以上的高血压病史。结论重度OSAHS对AD有一定影响，早期诊断及时治疗，对减缓AD的进程和降低其病死率，改善AD的预后具有重要的临床意义。
Objective To analyze the clinical features of obstructive sleep apnea-hypopnea syndrome （ OSAHS） with initial diagnosis of aorta dissection （ AD ） and therefore to improve its diagnosis. Methods The clinical data of 6 cases of AD with OSAHS were retrospectively analyzed. Results There were six male cases of obesity whose average body mass index （BMI） was 32.72 ± 3.57,with an average age of （43.83 ± 2.14） and the leading symptoms were daytime hypersomnolence, nocturnal wake by suffocation and habitual snoring. ESS was （13.83 ± 2.14） , apnea hypopnea index（AHI） was ≥62/h[ on averaga of （73.35 ±9.16） /h] ,the lowest pulse oxygen saturation （ LSpO2 % ） was （ 58.67 ± 10.95 ） % , time of oxygen saturation level lower than 90% （ min ） [ T90 （ min ） ] was （ 244.20 ± 144.74 ） min, the percent of the total time with oxygen saturation level lower than 90% （ TS90% ） was 54.48 ± 30.18. They had more than two years history of hypertension. Conclusion Severe OSAHS affects the prognosis of AD. Early diagnosis and timely treatment can delay the progress of AD and lower death rate, with an important significance in improving the prognosis of AD.
出处
《中国综合临床》
北大核心
2008年第6期574-576,共3页
Clinical Medicine of China
