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分子辐射生物剂量计发展潜势

Development potential on molecular radiation biological dosimeter
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摘要 生物剂量估算无论在辐射事故或职业流行病学调查等方面都是不可缺少的重要手段。以细胞遗传学方法为代表的生物剂量计经过半个多世纪的发展已经非常成熟，并被广泛应用。为了更好地应对辐射突发事件，寻找具有快速、简便、适合大范围人群应用的新型分子水平生物剂量计成为目前研究的热点。为此，着重介绍近年来研究期望价值比较高的分子水平生物指示剂。 Biological dose assessment is an important means on radiation accident and occupational epidemic investigation. Cytogenetic bio-dosimeter has been very matured and widely applied through half century development. In order to reply to radiation emergency better, it becomes hot point of research to search new type molecular bio-dosimeters which are provided with quick and simple operation as well as fit in with application of great range crowd. The biological indicators of molecular level which have development potential of radiation bio-dosimeter are reviewed.
作者 穆蕊 陈英
机构地区 军事医学科学院放射与辐射医学研究所放射毒理与辐射危害评价研究室
出处 《国际放射医学核医学杂志》 2008年第2期109-113,共5页 International Journal of Radiation Medicine and Nuclear Medicine
关键词 剂量效应关系 辐射 基因表达 辐射生物剂量计 Dose-response relationship, radiation Gene expression Radiation bio-dosimeter
分类号 R14 [医药卫生—公共卫生与预防医学]
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参考文献31

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国际放射医学核医学杂志
2008年 第2期

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