摘要
通过建立D-gal致亚急性衰老小鼠模型并给予西藏灵菇酸奶灌胃处理,测定小鼠心、肝组织中超氧化物歧化酶(SOD),过氧化氢酶(CAT)和谷胱甘肽过氧化物酶(GSH-Px)活性,丙二醛(MDA)的含量变化,来研究西藏灵菇酸奶的抗氧化作用及其机理.结果发现西藏灵菇酸奶能明显提高衰老模型小鼠心、肝组织SOD、CAT、GSH-Px活性,显著降低MDA的含量.证明西藏灵菇酸奶具有增强机体清除氧自由基能力,能提高抗氧化酶活性,从而发挥抗衰老作用.
Through establishing subacute aging mice model which was caused by D-gal and was filled stomach with Tibet Linggu Fungus yogurt,activities of Superoxide Dismutase（SOD）,Catalase（CAT） and Glutathione Peroxidase（GSH-Px）,the content changes of Malondialdehyde（MDA） in heart and liver tissue are determined to study the anti-oxidative effect and the mechanism of Tibet Linggu Fungus yogurt.Theses results show that Tibet Linggu Fungus yogurt can enhance activity of SOD, CAT,the GSH-Px and decrease the content of MDA obviously.It proved that Tibet Linggu Fungus yogurt is able to eliminate oxyen free radicals and can increase activities of antioxidases so as to play an anti-aging role.
出处
《佳木斯大学学报（自然科学版）》
CAS
2008年第3期430-432,共3页
Journal of Jiamusi University：Natural Science Edition
基金
佳木斯大学科研项目(S2007-31)
