摘要
目的比较七氟醚吸入麻醉与罗哌卡因腰-硬联合麻醉用于剖宫产术对新生儿Apgar评分的影响,探讨七氟醚用于产科麻醉的可行性。方法76例ASAⅠ或Ⅱ级、择期剖宫产的足月初产妇随机均分为两组:七氟醚组(S组)静注丙泊酚1.5mg/kg,并吸入3.5%(1·3MAC)七氟醚加3L/min氧吸入诱导后,插入喉罩,维持麻醉至胎儿娩出;对照组(R组)L2～3穿刺,蛛网膜下腔给予0.5%罗哌卡因10～15mg,切皮前给予丙泊酚1.5mg/kg。记录两组产妇的ECG、BP、SpO2等生命体征,记录给药至胎儿娩出的时间以及出生后即刻、5-min、10-min的Apgar评分。结果给药至胎儿娩出的时间两组均在5～10min。两组新生儿Apgar评分差异无统计学意义。七氟醚组有3例新生儿Apgar评分≤7分(7.9%);对照组有2例(5.3%)。结论3·5%七氟醚吸入麻醉用于剖宫产对新生儿Apgar评分无明显影响。
Objective To compare the effects of sevoflurane inhalation anesthesia with combined spinal-epidural block （CSEA） on Apgar scores of newborn after Ceasarean section and investigate the feasibility of sevoflurane inhalation anesthesia used for Caesarean section. Methods Seventy-six parturients were randomly and equally divided into two groups of sevoflurane inhalation anesthesia （group S） and CSEA （group R）. Anesthesia was indused with inhalation of 3.5% （1.3 MAC） sevoflurane in 3 L/min oxygen and intravenous injection of propofol 1.5 mg/kg under laryngeal marsk airway ventilation in group S. CSEA of L2 -3 was performed with spinal injection of ropivacaine 10-15 mg and propofol 1.5 mg/kg was injected iv before skin incision in group R. ECG, SpO2 ,BP,the time from drug administration to newborn delivery, and Apgar scores at 0.5 and 10 minutes after delivery were recorded. Results The time from drug administration to newborn delivery in two groups was 5 to 10 minutes. Apgar scores of two groups were similar. There were 3 cases （7.9%）with Apgar score≤7 in group S and 2 cases （5.3%） with that in group R. Conclusion There is no significant influence of 3.5 % （1.3 MAC） sevoflurane inhalation anesthesia on Apgar score of newborn after Caesarean section.
出处
《临床麻醉学杂志》
CAS
CSCD
2008年第4期307-308,共2页
Journal of Clinical Anesthesiology
