摘要
[目的]探讨乙型肝炎(乙肝)患者IL2、IL6、IL8、TNFα及其相关因素的临床意义。[方法]2005年6月至2007年7月,在滕州市2处医疗机构对143例乙肝病人和62名健康对照进行血清白细胞介素2(IL2)、白细胞介素6(IL6)、白细胞介素8(IL8)和肿瘤坏死因子α(TNFα)水平检测。[结果]各型乙肝患者血清IL2、IL6、IL8和TNFα水平明显高于健康对照(P<0.01);急性乙肝和重型乙肝患者血清IL2、IL6、IL8、TNFα水平明显高于慢性乙肝和乙肝肝硬变患者(P<0.01)。[结论]各型乙肝患者血清IL2、IL6、IL8、TNFα水平升高,病情越严重升高越明显。
[Objective]To study the levels of IL2,IL6,IL8 and TNFα in serum in patients with hepatitis B,explore the relation between IL2, IL6, IL8 and TNFα. [Methods]The level of IL2, IL6, IL8 and TNFαwere detected in 143 patients with hepatitis B and 62 healthy people （ control group）. [Results]The level of IL2, IL6, IL8 and TNFα in serum in patients with hepatitis B was significantly higher than that in healthy people（ P〈0.01） ,it also higher in patients with acute and severe hepatitis B than that in patients with chronic hepatitis B and cirrhosis of liver （P〈0.0）. [Conclusion]The level of IL2,IL6,IL8 and TNFα in serum in patients with any type of hepatitis B increased, the more serious of the disease, the more obvious of the increase level.
出处
《预防医学论坛》
2008年第4期309-310,共2页
Preventive Medicine Tribune
