期刊文献+

牙周病动物模型建立方法的研究进展 被引量:4

Recent Study in Periodontitis Animal Model
在线阅读 下载PDF
导出
摘要 牙周病是常见的口腔疾病,是造成中国成年人失牙的最重要原因。为进一步探讨牙周病的发病机制、病理学特点以及治疗效果和疗效的评价,动物模型被广泛应用。建立牙周病动物模型的方法,主要是用生物的、物理的、化学的和各种环境因子作用于实验动物。生物学因素包括细菌、病毒、寄生虫等致病原,通过接种而使正常动物发生疾病。文章就牙周病动物模型的建立方法进行综述。 Periodontitis is an usual type of nonnasality disease,which has been confirmed to be the vital reason that causes adults to loose teeth. To further discuss the pathogenesis, pathology characteristics, curative effect, experimental animals have been used widely. The method inducing periodontitis animal model contains biological ,physical ,chemical ,and various kinds of environment factors. Biological factors includes bacterium virus, parasite, and so on, which were inoculated in animals to induce the disease. This paper introduces the recent studies on periodontitis animal model.
作者 张嘉 梅陵宣
出处 《医学综述》 2008年第7期1035-1037,共3页 Medical Recapitulate
关键词 牙周病 动物模型 方法 Periodontitis Animal model Method
  • 相关文献

参考文献18

  • 1Egelberg J. Local effect of diet on plaque formation and development of gingivitis in dogs. I . Effect of hard and soft diets[ J]. Odontol Revy, 1965,16:31- 41.
  • 2孟焕新,谢昊,陈智滨,王洪君,章魁华,曹采方.小型猪实验性牙周炎的观察[J].中华口腔医学杂志,1996,31(6):333-336. 被引量:20
  • 3Achong R, Nishimura I, Ramachandran H, et al. Membrane type (MT) 1-matrix metalloproteinase(MMP) and MMP-2 expression in ligature-induced periodontitis in the rat [ J ]. J Periodontol,2003,74 (4) :494-500.
  • 4杨少强,廖旭辉,谢水林.牙周炎动物模型实验性的研究[J].国际医药卫生导报,2004,10(14):10-11. 被引量:8
  • 5Iwama A,Nishigaki N,Nakamura K,et al. The effect of high sugar intake on the development of periradicular lesions in rats with type 2 diabetes [ J ]. Dent Res,2003,82 (4) :322-325.
  • 6苏军,刘鲁川,毛永利,李楠,潘利峰,温秀杰.SD大鼠牙周炎动物模型的建立[J].牙体牙髓牙周病学杂志,2006,16(11):612-615. 被引量:25
  • 7Tomofuji T,Azuma T,Kusano H,et al. Oxidative damage of periodontal tissue in the mt periodontitis model :effects of a high-cholesterol diet[ J]. FEBS Lett ,2006,580( 15 ) :3601-3604.
  • 8Li CH, Amar S. Morphometrie, histomorphometric, and miemcomputed tomographic analysis of periodontal inflammatory lesions in a murine model[J]. J Periodontol,2007,78(6) : 1120-1128.
  • 9王仲杰,于江波.牙周炎动物模型研究[J].工企医刊,2006,19(2):18-20. 被引量:1
  • 10汪黎明,郭连美,瞿启文,李家麟,王慧中.牙周袋炎症的动物模型制备[J].第二军医大学学报,1997,18(2):185-186. 被引量:6

二级参考文献33

共引文献70

同被引文献62

引证文献4

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部