摘要
目的通过观察初治鼻咽癌患者放射治疗的毒副反应，比较分析调强放疗与常规放疗的差异。方法临床观察从2003年12月-2005年12月86例初治鼻咽癌患者放疗后出现的毒副反应，主要观察急性口腔粘膜反应、急性皮肤反应、血液毒性反应、张口受限、口干症。结果调强组患者的急性皮肤反应、口干、张口受限的症状明显低于常规组，有显著差异；口腔粘膜急性反应、血液毒性与常规组无明显差异。结论调强放疗可明显降低常规放疗的毒副反应。
Objective To compare the toxicity of radiotherapy for newly diagnosed Nasopharygeal Carcinoma using conventional or Intensity Modulated Radiation Therapy （IMRT） technique. Methods Eighty-six patients with newly diagnosed nasopharygeal carcinoma were treated with conventional radiotherapy or IMRT from December 2003 to December 2005. Acute toxicities including acute skin reaction.acute radiation-induced mucositis,hematological toxicity.trismus and xerostomia were documented. The severity of toxicity between the two groups （conventional and IMRT group） were compared. Results The incidence of the acute skin reaction, xerostomia and trismius in conventional radiotherapy group was significant higher than in the IMRT group. The incidence of Mucositis and hematological toxicity was similar in the two groups. Conclusions IMRT technique can significantly reduce the incidence of acute toxicity compared of conventional radiotherapy in Nasopharygeal Carcinoma.
出处
《齐齐哈尔医学院学报》
2007年第24期2948-2951,共4页
Journal of Qiqihar Medical University
关键词
鼻咽癌
调强放射治疗
常规适形放疗
毒副反应
Nasopharyngeal carcinoma Intensity-modulated radiotherapy Conventional conformal radiotherapy Toxic side reaction
