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TIPS中8mm直径覆膜支架应用的临床研究 被引量:34

Clinical study on transjugular intrahepatic portosystemic shunt creation with 8 mm diameter covered stent-graft
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摘要 目的评价在TIPS中应用8mm直径覆膜支架的临床效果。方法对19例伴有食管胃底静脉曲张破裂出血和(或)难治性腹水的门脉高压症患者行TIPS术,术中应用8mm直径的覆膜支架,术后观察临床症状改善程度,并进行定期影像学和实验室检查,以评价疗效。结果所有患者均成功完成TIPS术,技术成功率100%,术中未出现并发症。术后平均随访13.5个月(2.7~28个月),1例(1/19,5.3%)原有肝性脑病加重;2例(10.5%)再次出血;腹水改善及治愈率为66.7%(12/18);16例患者进行了6个月的随访,初次开通率100%,8例患者随访12个月,初次开通率87.5%。结论在TIPS术中应用8mm直径覆膜支架在保证有效分流量,提高术后分流道开通率的同时,可以降低肝性脑病的发生率。 Objective To evaluate the clinical results of transjugular intrahepatic portosystemic shunt (TIPS)creation with 8 mm diameter covered stem-graft. Methods Ninteen concecutive patients with portal hypertension underwent TIPS creation with 8 mm diameter covered stem-graft for variceal bleeding and/or refractory ascites. Evaluation of the results through observing the improvement of clinical symptom and periodic follow up was carried out. Results Technical success achieved in all patients reaching 100% without related complications. Median follow-up was 13.5 months(ranged, 2.7 - 28 months). One case (1/19,5.3%)showed aggravation of hepatoencephalopathy and 2 others (2/19, 10.5%)revealed rebleeding. The primary patency rate was 100%(16/16)after 6 months, and 87.5%(7/8)after 12 months. Improvement or resolved rate of ascites was 66.7% (12/18). Conclusion TIPS creation with 8 mm diameter covered stent-graft can degrade the incidence of hepatic encephalopathy, improve the rate of TIPS patency and keeping the effective shunt flow.
作者 梁松年 徐克
出处 《介入放射学杂志》 CSCD 2008年第2期98-101,共4页 Journal of Interventional Radiology
关键词 经颈静脉门腔静脉分流术 覆膜支架 肝性脑病 TIPS Covered stent-graft Hepatic encephalopathy
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