摘要
目的:评价用保存角膜行植床带周边后板层的大植片穿透性角膜移植术(PKP)的临床疗效和并发症。方法:回顾性分析2003-12/2006-12我院收治的角膜严重病变的患者108例(116眼),其中用保存角膜联合植床带周边后板层大植片穿透性角膜移植治疗63眼为改良组用传统手术方式新鲜角膜植片移植治疗53眼。比较两组术后的角膜植片、排斥反应及并发症情况。结果:改良手术组治疗的63眼中,8眼(12.7%)发生不同程度的植片排斥反应、术后浅前房2眼(3.2%)、虹膜前粘连1眼(1.6%)、继发青光眼2眼(3.2%);传统手术组治疗的53眼中,植片排斥反应15眼(28.3%)、术后浅前房11眼(20.8%)、虹膜前粘连8眼(15.1%)、继发青光眼6眼(11.3%)。两组的术后的植片排斥反应率和并发症有显著差异(P<0.05)。结论:用保存角膜联合植床带周边后板层行大植片穿透性角膜移植术是降低术后免疫排斥反应,延长植片的存活时间的有效方法。
AIM： To evaluate the clinical effects and complications of large-graft penetrating keratoplasty （PKP） using storage cornea by applying peripheral posterior lamella in the recipient＇s bed.METHODS： A total of 108 cases （116 eyes） with severe keratopathy admitted into our hospital between December 2003 and December 2006 were retrospectively analyzed. 63 eyes in modified group were treated with posterior lamellar large-graft PKP using storage cornea, while 53 eyes were treated with traditional PKP using fresh cornea. The incidence of graft immune rejection and complications were compared between two groups after the operation. RESULTS： Among ,63 eyes treated by storage cornea in modified group, 8 eyes （12.7%） had immune rejection; 2 eyes （3.2%） had shallow anterior chamber; 1 eye （1.6%） had anterior synechia; 2 eyes （3.2%） had secondary glaucoma. Among 53 eyes treated by fresh cornea in traditional group, 15 eyes （28.3%） had immune rejections; 11 eyes （20. 8%） had shallow anterior chamber; 8 eyes （15.1%） had anterior synechia; 6 eyes （ 11. 3%） had secondary glaucoma. There were statistically significant differences between two groups in the aspect of immune rejection and complications after the operation （P〈0.05）. CONCLUSION; PKP using storage cornea with peri-pheral posterior lamella in the recipient＇s bed is an effective way to reduce the incidence of graft immune rejections and prolong the corneal survival time.
出处
《国际眼科杂志》
CAS
2008年第1期161-163,共3页
International Eye Science
