摘要
目的观察五味子与黄药子合用时,对黄药子所致生化及肝肾病理改变的缓解作用。方法对比黄药子组、拮抗组小鼠在给药60d后观察肝脏生化指标、病理。结果拮抗各剂量组对相应剂量黄药子所致的ALT升高及病理改变有明显的缓解和抑制作用。
Objective Purpose When Schisandra chinensis （Turcz.） Baill and Dioscorea bulbifera L. are applied together observe the capability of lysis on biochemical and liver kidney pathology change caused by Dioscorea bulbifera L Method Compare liver biochemical index and pathology of mice in Dioscorea butbifera L. group with those in group after 60 days of dosing, Results All dose levels of group demonstrated obvious lysis and containment capabilities against elevated ALT and pathology change caused by Dioscorea bulbifera L at the corresponding dose ranges.
出处
《临床药物治疗杂志》
2008年第1期29-34,共6页
Clinical Medication Journal
基金
中国中医科学院广安门医院所级科研课题
课题编码:2004S82
关键词
黄药子
五味子
拮抗
肝肾损害
Dioscorea bulbifera L.
Schisandra chinensis （Turcz.） Bail
detoxification
heptatic and renal toxicity
