摘要
目的探讨临床特征及术前各种辅助检查在判断甲状腺结节良恶性方面的价值。方法对1999—2004年上海交通大学医学院附属瑞金医院1367例甲状腺结节手术患者的临床资料进行回顾性分析。结果1367例甲状腺结节中良性病变1141例(83.47%),恶性病变226例(16.53%)。辅助检查中,B超检查敏感度、特异度、诊断准确度分别为2.11%,99.27%,83.19%;CT检查分别为22.58%,86.00%,70.99%;细针穿刺(FNA)细胞学检查分别为65.12%,95.08%,82.69%。多因素回归分析结果显示,患者较年轻,存在实性、质地偏硬的结节,结节伴钙化或颈部无痛性淋巴结肿大者恶性可能性较大。结论临床症状、体征、甲状腺B超及FNA对恶性甲状腺病变均有一定的提示作用,尤其是FNA在判断结节性质方面具有较高的敏感度、特异度及诊断准确度。
Objective To evaluate the utility of clinical characters and variant exanfinations in discriminating benign from malignant thyroid lesions before operation. Methods We had retrospectively analyzed 1367 cases of thyroid nodule that were operated in Ruijin Hospital from 1999 to 2004. Results Clinical symptoms and signs, uhrasonography and fine needle aspiration（FNA） were all useful in indicating malignant thyroid lesions, especially FNA ,whose sensitivity, specificity and diagnostic accuracy were 65.12% ,95.08% and 82. 69% , respectively. By logistic regression analysis, the thyroid nodule of young patients or solid or hard nodules,or nodules hard, or accompanied with calcification or nonached lymphadenectasis might be maligment nodules. At this time, FNA shoud be performed. Conclusion The above findings emphasize the importance of reviewing carefully and utilizing effectively the clinical information of each patient.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2007年第23期1842-1845,共4页
Chinese Journal of Practical Internal Medicine
关键词
甲状腺结节
术前
性质
Thyroid nodules
Presurgical
Property
