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心房颤动患者P波离散度的临床观察及胺碘酮干预 被引量:2

The clinicd observation of P wave dispersion and therapeutic effect of amiodarone in patients with paroxysmal atrial fibrillation
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摘要 目的:探讨P波离散度能否预测阵发性心房颤动(AF)患者发生的概率及胺碘酮干预的评价。方法:选择110例冠心病(CHD)患者,其中观察组55例为CHD并AF患者;对照组55例无AF的CHD患者。测量最大P波时限(Pmax),最小P波时限(Pmin)及P波离散度(Pd),并对观察组患者给予胺碘酮干预后观察Pd变化。结果:Pmax观察组高于对照组,有显著性差异(P<0.001),Pmin观察组低于对照组(P>0.05)。观察组经胺碘酮干预后43例转为窦性心律(占78.1%),25例Pd≤40ms(占45.5%)。结论:Pd是心房颤动的独立预测指标,胺碘酮对房颤患者Pd有一定的干预作用。 Objective: To investigate the association of P wave dispersion (Pd) with the occurrence rate of paroxysmal atrial fibrillation (PAF) and the efficacy with amiodarone treatment . Methods :110 patients were evaluated. 55 patients with PAF served as A group and Others without PAF as B group. Electrocardiography was recorded for all the patients on admission. Then Pd , maximal and minimal P wave duration (Pmax and) were calculated. Results:Comparde with B group,the Pmax of electrocardiography of A group was obvionsly higher (P〈0. 001),and the Pmin was lower (P〉0.05), The electrocardiography of 43 patients (78.1%) was changed into sinus rhythm and the Pd of 25 patients (45.5%) was lower than 40ms in the 55 PAF patients after treatment with amiodarone. Conclusion:Pd is a sensitive and specific predictor of PAF occurrence in patients with heart disease and can be used for the drug evaluation of anti-atrial arrhythmia.
出处 《陕西医学杂志》 CAS 北大核心 2007年第12期1601-1603,共3页 Shaanxi Medical Journal
关键词 心房颤动/治疗 胺碘酮 @P波离散度 Atrial fibrillation/therapy Aniodarone @P wave dispersion
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参考文献5

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同被引文献14

  • 1牛凡,黄从新,江洪,杨波,郭文玲,陈云霞,靳春荣,刘卓敏.胺碘酮和索他洛尔治疗心房颤动的随机对比研究[J].中华医学杂志,2006,86(2):121-123. 被引量:22
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  • 4Kalifa J,Jalife J,Zaitsev AV,et al.Intra-atrial pressure increases rate and organization of waves emanating from the superior pulmonary veins during atrial fibrillation.Circulation,2003,108:668-671.
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  • 7Tuseth V,Jaatun HJ,Dickstein K,et al.Amiodarone infusion in the treatment of acute atrial fibrillation or flutter:high versus low dose treatment.Heart,2005,91(7):964--965.
  • 8Komatsu T,Nakamura S,Suzuki O,et al.Long-term prognosis of the patients with paroxysmal atrial fibrillation depends on the response to antiarrhythmic therapy.Circ J,2004,68:729.
  • 9Komatsu T,Sato Y,Tachibana H,et al.A randomized crossover study on the long-term effects of pilsicainide and cibenzoline in preventing recurrence of symptomatic paroxysmal atrial fibrillation:Influence of the duration of arrhythmia before therapy.Circ J,2006,70:667.
  • 10Kalifa J,Jalife J,Zaitsev AV,et al.Intra-atrial pressure increases rate and organization of waves emanating from the superior pulmonary veins during atrial fibrillation.Circulation,2003,108:668.

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