摘要
目的研究布地奈德雾化溶液吸入治疗对喘息性支气管炎患儿呼吸道阻力(AR)的影响。方法喘息性支气管炎患儿56例随机分为A组(常规+布地奈德雾化溶液吸入治疗)和B组(常规治疗),同时选取同期保健门诊同年龄组正常幼儿30例为对照组。应用Microloop肺功能仪加载的MicroRint传感器分别对各组儿童治疗前后的AR进行监测。结果喘息性支气管炎患儿急性期与对照组相比,AR明显增高(P<0.01);治疗2周后,A、B组AR均显著降低(Pa<0.001);但A组AR降低程度更明显,与对照组相比无明显差异;B组AR仍高于对照组。结论喘息性支气管炎患儿急性期AR明显升高;加用布地奈德雾化溶液吸入治疗可迅速减低患儿AR,缩短病程。
Objective To examine the changes of the airway resistance（AR） in asthmatic bronchitis children before and after budeso-nide-solution inhaled therapy.Methods Fifty-six cases of asthmatic bronchitis children were randomly divided into A（regular treatment＋budesonide-solution inhaled） and B groups（regular treatment）,and 30 normal children at the same age as control group.The AR was eva-luated by Microloop lung function meter with MicoroRint sensor.The changes of AR were compared within above 3 groups.Results AR in asthmatic bronchitis children increased significantly compared with normal children.After 2 weeks treatment,AR decreased significantly in both A and B groups compared with that of 2 groups before therapy,AR in A groups declined to normal control level,but still kept higher level in B groups.Conclusions AR in asthmatic bronchitis children increase significantly.The effect of Budesonide-solution in asthmatic bronchitis children is partly via reducing AR to improve ventilated condition.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2007年第4期299-300,共2页
Journal of Applied Clinical Pediatrics
