摘要
目的:在中医及现代医学理论指导下,运用现代临床实验和检查手段,探索研究中药治疗乳腺增生病的新方法。方法:收集119例诊断为乳腺增生病患者,随机分2组,治疗组61例予中药消癖方口服,对照组58例予口服三苯氧胺20mg/天,治疗6个月后,对比治疗前后卵泡期血液中激素(E2、P、PRL)水平及乳腺高频X线影像改变,评价疗效。结果:治疗组有效率91.80%,对照组有效率84.48%。经统计学分析,治疗组疗效与三苯氧胺组等效(P>0.05),同时两组在乳腺高频X线摄影影像学变化上和调节E2水平的作用无显著性差异(P>0.05);但治疗组调节PRL,对冲任失调型疗效优于对照组,且毒副反应小,差异有显著性(P<0.05)。结论:中药治疗乳腺增生病无毒副作用、临床疗效好;将观察内分泌激素水平的调节变化及乳腺X线影像学改变引入中药研究,为临床研究提供一些新的思路。
Objective = Under the guidance of TCM and modern astosurgery, study the Fibrocystic disease of breast （ F.C.D ）. Methods ： 61 cases diagnosed as F.C.D were randomly selected and treated with traditional Chinese medicine; and 58 cases were selected and treated with TAM 20mg/d for 6 months. All of them have examination level of sex hormones and mammography before and after treatment. Results ： All the patients were treated for 6 months. In the TCM group, the total effective rate being 91.80%, while in the TAM group, the corresponding numbers were 84.48%, comparison between the two groups, the total effective rates showed no difference （ P〉0.05 ）, TCM and TAM could adjust the level of sex hormones and recover the normal signs in the X-ray （ P〉0.05 ）, but TCM group was well tolerated （ P〈0.05 ）.Conclusion ： Treating F.C.D with traditional Chinese medicine is well tolerated and results in the same clinical effective rate of TAM. The study providing a new measure in clinic research.
出处
《辽宁中医药大学学报》
CAS
2007年第6期137-139,共3页
Journal of Liaoning University of Traditional Chinese Medicine
关键词
乳腺增生病
孕激素
催乳素
雌激素
放射摄影术
临床研究
中医药
F.C.D
progesterone
estrogen
prolactin
mammography
clinical research
traditional Chinese medicine
