摘要
哮喘(asthma)是一种常见的呼吸系统疾病,到目前为止哮喘的发病机制仍然不十分明确。蛋白质组学(proteomics)的研究进展,为哮喘的发病机制及治疗的研究带来了新的曙光。目前,蛋白质组学技术在哮喘研究中的应用主要包括快速鉴定变应原、筛选蛋白标记物等。本文就近年来蛋白质组学技术在支气管哮喘上的研究进展及应用现状作一综述。
Asthma is one of the most common diseases of respiratory system. The pathogenesy of asthma is still unclear. With the development of proteomics research, many differentially expressed proteins and peptides were identified in serum and tissues as candidate allergens,biomarkers and therapeutic targets. This paper reviewed the development of proteomics research in asthma nowadays.
出处
《国际呼吸杂志》
2007年第21期1645-1648,共4页
International Journal of Respiration