摘要
目的探讨妊娠合并多器官功能障碍综合征(MODS)患者的原发病因及其死亡原因。方法对2000年1月至2006年12月广州医学院第三附属医院收治的206例妊娠合并 MODS 患者的原发病因及其死亡原因进行回顾性分析。结果 (1)原发病因:206例妊娠合并 MODS 患者主要原发病因依次为产后出血63例(30.6%),重度子痫前期及子痫60例(29.1%),妊娠合并肝炎23例(11.2%),妊娠合并心脏病11例(5.3%),异位妊娠12例(5.8%)。(2)死亡原因:206例妊娠合并MODS 患者中死亡44例,死亡的主要原发病因为产后出血11例(17.5%,11/63),重度子痫前期及子痫7例(11.7%,7/60),妊娠合并心脏病7例(63.6%,7/11),妊娠合并肝炎6例(22.7%,6/23),异位妊娠5例(41.7%,5/12)。结论妊娠合并 MODS 原发病因中以产科因素为主;不同原发病器官功能障碍的死亡率有明显差异,其中原发病器官为心脏、脑的死亡率较高。提示临床工作中可根据不同原发病器官采取相应的预防和治疗措施。
Objective To analyze 206 cases of pregnant women with multiple organ dysfunction syndrome （MODS） due to different primary diseases and the prognosis. Method A retrospective study was conducted of 206 cases of pregnant women with MODS who were treated during January 2000 to December 2006 in the Third Affiliated Hospital of Guangzhou Medical College, regarding their primary disease and prognosis. Results Fourty-four cases among the 206 pregnant women with MODS died. The main primary causes were postpartum hemorrhage in 63 cases （ 30. 6% ）, severe preeclampsia or eclampsia 60 cases （29. 1% ）, pregnancy with hepatitis C in 23 cases （ 11.2% ）, pregnancy with heart disease in 11 cases （5.3%）, 12 cases of ectopic pregnancy （5.8%）. The mortality was mainly because of pregnancy complicated with heart disease （ 63.6% ）, ectopic pregnancy （ 41.7% ）, pregnancy with hepatitis （22. 7% ）, of postpartum hemorrhage （ 17.5% ） and severe preeclampsia-eclampsia （ 11.7% ） . The difference was statistically significant （ P 〈 0. 05 ）. Conclusion Primary diseases leading to pregnancy complicated with MODS are mainly due to obstetric factors, accounting for 65.05%. However, dysfunction of different organs can result in a significant difference in mortality, mortality from primary diseases of the heart and brain were higher. It is suggested that preventative and therapeutic measures should be taken according to different primary disease organs.
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
2007年第10期655-657,共3页
Chinese Journal of Obstetrics and Gynecology
关键词
妊娠并发症
多器官功能衰竭
死亡原因
Pregnancy complications
Multiple organ failure
Cause of death
