摘要
目的研究病毒性脑炎患者血清与脑脊液标本中病毒特异性抗体IgM阳性率的差异,并探讨其诊断意义。方法回顾同期进行了血清与脑脊液检测病毒特异性抗体IgM的89例病毒性脑炎住院患者资料,统计抗体阳性率,比较:(1)两种标本中病毒特异性抗体阳性率的差异;(2)一种标本检测与两种标本同时检测病毒特异性抗体阳性率的差异。结果(1)血清标本病毒特异性抗体的阳性率为53.93%,脑脊液标本病毒特异性抗体的阳性率为34.83%,两者比较有显著统计学差异(P<0.025)。(2)两种标本同时检测病毒特异性抗体阳性率为71.91%,与任何一种标本检测的阳性率比较,有显著统计学差异(P<0.02)。结论(1)检测血清中病毒特异性抗体可获得较脑脊液高的阳性率;(2)两种标本同时检测病毒特异性抗体是一种提高病毒性脑炎病原学诊断阳性率的有效方法。
Objective To investigate the positive rate and diagnostic value of specific antibody IgM in serum and cerebrospial fluid （CSF） of the patients with viral encephalitis. Motheds The specific antibody in serum and CSF of 89 patients with viral encephalitis were determined by ELIS . All the data were conducted retrospective analysis, they included the positive rate of antibody in serum , CSF or the two specimens which were determined at the same time . Results The positive rate of antibody in serum was 53.93% and 34.83% in CSF .There was significant difference between the two specimens （P〈0.025）. as two specimens were determined at the same time the positive rate was 71.91%, and higher than either of the former （P〈0.02）. Conclusin Determining specific antibody in serum can acquire higher positive rate than that in CSF ,and it is an effective method . If the two specimens were determined at the same time ,that the positive rate of pathogenic diagnosis in viral encephalitis could be increased.
出处
《实用心脑肺血管病杂志》
2007年第8期580-582,共3页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
