摘要
目的：研究医院感染超广谱β-内酰胺酶（ESBLs）肺炎克雷伯菌的基因型。方法：收集分离鉴定菌株，通过K—B法药敏实验初筛以确认产ESBLs菌株，并对ESBLs基因进行初步分型。结果：17株肺炎克雷伯菌产生的ESBLs以CTX-M-3、CTX-M-15、CTX-M-22为主要基因型，其中8株为CTX—M-3型；6株为CTX-M-22型；1株为CTX-M-15型；1株同时产CTX-M-3、CTX-M-22；1株同时产CTX-M-15、CTX-M-22型。结论：我院肺炎克雷伯菌临床分离株中的ESBLs基因型以CTX-M型酶为主。
Objective To study genotyping of plasmid-mediated extended spectrum beta lactamases （ESBLs）-producing Klebsiella pneumoniae from nosocomial infections. Methods ESBLs-producing strains from clinical isolates of Klebsiella pneumoniae were screened by K-B method. And then ESBLs gene typing initially was performed. Results CTX-M-3, -15, -22 type were common ESBLs genotypes produced by 17 K. pneumoniae strains, in which 8 strains were CTX-M-3 type, 6 strains CTX-M-22, 1 strain CTX-M-15, 1 strain CTX-M-3 and CTX-M-22, as well as 1 strain CTX-M-15 and CTX-M-22. Conclusion The most common genotype of ESBLs-producing K. pneumoniae is CTX- M type.
出处
《国际检验医学杂志》
CAS
2007年第8期691-692,共2页
International Journal of Laboratory Medicine
关键词
肺炎克雷伯菌
基因型
Klebsiella pneumoniae
Genotyping
