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镉对豚鼠乳头肌动作电位的影响 被引量：1

镉对豚鼠乳头肌动作电位的影响
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摘要 目的:研究氯化镉(CdCl2)对正常豚鼠心室乳头肌细胞动作电位(AP)的影响。方法:用常规细胞内微电极方法记录乳头肌细胞AP。结果:在生理条件下,CdCl2可使APo期振幅(APA)和最大除极速率(Vmax)降低,动作电位时程(APD)缩短,且具有剂量依赖性。结论:CdCl2可使心室肌AP的APA、Vmax、APD发生改变,提示CdCl2有抑制Na+、Ca2+内流和激活K+外流作用。
作者 龚顺开 余国冰 李坤 郑倩
机构地区 川北医学院生理教研室 南京中医学院生理教研室
出处 《中国应用生理学杂志》 CAS CSCD 北大核心 2007年第3期291-292,384,共3页 Chinese Journal of Applied Physiology
关键词 镉 心室乳头肌 动作电位 cadmium ventricular myocardium action potential
分类号 R332 [医药卫生—人体生理学]
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参考文献5

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共引文献5

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  • 1武煜,顾振纶.茶多酚的药理学作用及其机制研究进展[J].中成药,2005,27(6):722-725. 被引量：40
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中国应用生理学杂志
2007年 第3期

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