摘要
动脉粥样硬化是脑血管病的病理学基础。业已证实,慢性炎症反应是动脉粥样硬化发生和发展过程中的一个极为重要的因素。大量临床研究表明,炎症因子,如C-反应蛋白、肿瘤坏死因子-α、转换生长因子-β以及白细胞介素-10水平增高与缺血性卒中的发生和发展密切相关,有望成为缺血性卒中早期检测和预后判断的生物学标志。
Atherosclerosis is the pathology basis of cerebrovascular diseases. It has been demonstrated that the chronic inflammatory response is an very important factor in the occurrence and development of atherosclerosis. A number of clinical trials have suggested that inflammatory factors such as the elevated levels of C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), transforming growth factor-β (TGF-β) and interleukin-10 (IL-10) are closely associated with the occurrence and development of ischernic stroke. They may become the biological markers in early detection and predicting the prognosis of ischernic stroke.
出处
《国际脑血管病杂志》
2007年第6期464-468,共5页
International Journal of Cerebrovascular Diseases