摘要
目的：观察复方甘草酸苷在尖锐湿疣中的临床疗效,以及对降低尖锐湿疣复发率的作用.方法：120例尖锐湿疣患者按随机化原则分配至治疗组与对照组,治疗组采用高频电针烧灼患处皮疹,术后静脉滴注复方甘草酸苷注射液20～40mL·d^-1,10d为1个疗程,可重复2～3疗程,后改用复方甘草酸苷片维持,1片·次^-1,3次·d^-1,维持至术后第3个月.对照组仅采用高频电针烧灼患处皮疹.结果：治疗组的CD3指标升高高于对照组（治疗组11.36/对照组4.45,P＜0.001）,复发病例少（治疗组39例/对照组50例,P＜0.05）,无明显副作用.结论：复方甘草酸苷可升高尖锐湿疣患者细胞免疫CD3值,减少复发.
OBJECTIVE：To observe the clinical therapeutic effect of compound glycyrrhizin in the treatment of condyloma acuminatum so as to reduce its relapse rate.METHODS： A total of 120 patients with condyloma acuminatum were randomly divided into two groups： for the trial group, the rash in the Par.all.was cauterized with electrocautery, then the patients were treated with intravenous compound glycyrrhizin 20--40mL · d^ -1 for 2--3 repeated courses of treatment（a course of treatment = 10d）, followed by oral administration of compound glycyrrhizin tablet（1 tablet each time tid） until the 3rd month after operation; while the control group was only treated with electrocautery for the rash in the Par.all.RESULTS： In the trial group compared with the control group, the increase of CD3 was higher（11.36 vs.4.45, P〈0.001）, the relapse rate of condyloma acuminatum was less（39 cases/50 cases, P 〈0.05）, and no significant adverse effects were noted .CONCLUSION： Compound glycyrrhizin can be used as a therapy for condyloma acuminatum for it can help elevate cell immunity CD3 value,reduce relapse rate and shorten the time of therapy.
出处
《中国药房》
CAS
CSCD
北大核心
2007年第20期1565-1566,共2页
China Pharmacy
关键词
复方甘草酸苷
尖锐湿疣
免疫
复发
Compound glycyrrhizin
Condyloma acuminatum
Immune
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