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抗辐射菌中DNA损伤修复主要基因群的研究进展 被引量：2

Research Progress on Central Genes of DNA Repair in Radiation Resistant Deinococcus radiodurans
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摘要 抗辐射红色球菌对电离辐射具有很高的放射线抵抗性,该菌具有惊人的DNA的二条链切断的修复能力,由辐射等引起的切断损伤DNA在几至十几小时内能高效正确地进行完全修复。在对切断的双链DNA进行修复时,除了大肠杆菌等生物在切断的双链DNA修复时出现的蛋白质以外,还有该菌所特有的修复蛋白质也参与修复。本文对该菌所特有的DNA二条链的切断损伤修复的主要基因及其相互作用进行了简要介绍。 Radiation resistant Deinococcus radiodurans has high radioresistance to ionizing radiation and astonished DNA strand break damage repair ability. DNA strand break damage caused by irradiation can be repaired correctly and effectively in a certain time. Duing DNA strand break repairs, the same damage repair protein that appeared in E. coli DNA damage repairs appeared, and peculiar repair protein of Deinococcus radiodurans also participate in the repairs. In this paper, these central repair genes and their interaction were concisely introduced.
作者 施美星 屠振力
机构地区 浙江环龙环境保护公司 浙江大学动物科学学院
出处 《激光生物学报》 CAS CSCD 2007年第3期374-378,F0003,共6页 Acta Laser Biology Sinica
基金 教育部留学回国人员科研启动基金资助项目(J20040269) 浙江省教育厅基金项目(G20040392) 浙江省自然科学基金(Y305224) 浙江省"钱江人才计划"项目(2006R10001)
关键词 抗辐射菌 辐射抗性 DNA损伤修复 基因群 Deinococcus radiodurans radioresisitance DNA damage and repair central genes
分类号 Q937 [生物学—微生物学] R811.5 [医药卫生—放射医学]
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参考文献40

  • 1ADNERSON A W,NORDAN H C,CAIN R F,el al.Studies on a Radio-resistant Micrococcus Isolation,M0rphology,Cultural Characteristics.and Resistance to Gamma Radiation[J].Food Techmol,1956,10:575-578.
  • 2MOSELEY B E,MATHNGLY A.Repair of Irradiated Transforming Deoxyribonucleic Acid in Wild-type and a Radiation-sensitive Mutant of Micrococcus radiodurans[J].J Bacteriol,1971,105:976-983.
  • 3LEVIN-ZAIDMAN S,ENGLANDER J,SHIMONI E,et al.Ringlike Structure of the Deinococcus radiodurans Genome:A Key to Radioresistance?[J].Science,2003,299:254-256.
  • 4BATTISTA J R.DNA Repair in Deinococcus radiodurans//NICKOLOFF J A,HOEKSTRA,M F.DNA Damage and Repair[M].Totowa NJ:Humana Press,1998,287-303.
  • 5LIN J,QI R,ASTON C,et al.Whole Genome Shotgun Optical Mapping of Deinococcus radiodurans[J].Science,1999,285:558-1562.
  • 6KITAYAMA S,MATSUYAMA A.Possibility of the Repair of Double-strand Scissions in Micrococcus radiodurans DNA Caused by Gamma-rays[J].Biochem Biophys Res Commun,1968,33:418-422.
  • 7SMITH K C,MARTIGNONI K D.Protection of Escherichia coli Cells against the Lethal Effects of Ultraviolet and x Irradiation by Prior x Irradiation:a Genetic and Physiological Study[J].Photochem Photobiol,1976,24:515-523.
  • 8BRIM H,MCFARLAN S C,FREDRICKSON J K,et al.Engrineering Deinococcus radiodurans for Metal Remediation in Radioactive Mixed Waste Environments[J].Nat Biotechnol,2000,18:85-90.
  • 9WOOD R D,MITCHELL M,SGOUROS J,et al.Human DNA Repair Genes[J].Science,2001,291:1384-1289.
  • 10MINTON KW.Repair of Ionizing Radiation Damage in the Radiation Resistant Bacterium Deinococcus radiodurans[J].Mutat Res,1996,363:1-7.

同被引文献35

  • 1屠振力,施美星.重离子射线照射后抗辐射菌基因组DNA的损伤修复[J].微生物学杂志,2006,26(6):19-22. 被引量：3
  • 2周庆,陈微微,张新觉,徐虹,徐步进,华跃进.耐辐射球菌不存在经典的SOS反应[J].科学通报,2007,52(5):534-539. 被引量：2
  • 3Anderson AW, Nordan HC, Can RF, et al. Studies on a radio-resistant micrococcus Isolation, morphology, cultural characteristics, and resistance to gamma radiation[J]. Food Techmol, 1956,10:575-578.
  • 4Lange CC. Wackett LP, Minton KW, et al. Engineering a recombinant Deinococcus radiodurans for organopollutant degradation in radioactive mixed waste environments [J]. Nat Biotechnol, 1998,16(10): 929-933.
  • 5Cox MM, Battista JR. Deinococcus radiodurans- the consummate survivor[J]. Nat Rev Microbiol, 2005, 3(11 ):882-892.
  • 6White O, Eisen JA, Heidelberg JF, et al. Genome sequence of the radioresistant baeterium Deinococcus radiodurans R I [J]. Science, 1999, 286(5444): 1571-1577.
  • 7Makarova KS, Aravind L, Wolf YI, et al. Genome of the extremely radiation-resistant bacterium Deinococcus radiodurans viewed from the perspective of comparative genomics [J]. Microbiol Mol Biol Rev, 2001,65( 1 ):44-79.
  • 8Krasin F, Hutchinson F. Repair of DNA double-strand breaks in Escherichia coil, which requires recA function and the presence of a duplicate genome[J]. Mol Biol, 1977,116(1 ):81-98.
  • 9Bauche C, Laval J. Repair of oxidized bases in the extremely radiation-resisitant bacterium Deinococcus radiod urans [J]. J Bacteriol, 1999, 181(1):262-269.
  • 10Pitcher RS, Brissett NC, Doherty AJ. Nonhomologous end-joining in bacteria: a microbial perspective [J]. Annu Rev Microbiol, 2007,61: 259-282.

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激光生物学报
2007年 第3期

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