摘要
目的应用脉冲组织多普勒成像技术(pulse-wave doppler yissue imaging,PWDTI)评价急性心肌梗死(acute myocardial infarction,AMI)不同治疗方案后局部室壁功能的变化情况。方法 AMI 患者72例,分为3组,经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)组30例,溶栓组27例,保守治疗组15例。采用PWDTI 定量测定患者治疗一周时局部室壁运动速度同时结合常规16节段超声心动图资料,并在梗死后1个月及3个月进行随访。结果 72例中共出现异常室壁运动节段382个,3组间异常室壁节段,PCI 和溶栓组在1周时收缩波峰速度(peak systolic velocity,Vs),收缩波加速度(acceleration of S wave,ACCs)及舒张早期峰速度/舒张晚期峰速度(E/A)均高于保守治疗组,在治疗后1个月到3个月时 Vs、收缩波时间速度积分(systolic velocity-timeintegral,VTIs)、ACCs 及 E/A 明显高于保守治疗组,但 PCI 组各项指标与溶栓组比较无统计学差异。结论PWDTI 评估 AMI 不同治疗对心脏局部室壁功能的影响,提示 PCI 或溶栓治疗优于保守治疗。
Objective To evaluate the regional wall motion change after different therapeutic protocols in acute myocardial infarction （AMI） patients by pulsed-wave tissue doppler imaging （PWDTI）. Methods Seventy-two patients were divided into three groups： percutaneous coronary intervention group （PCI, n= 30）, thrombolysis group （n=27） and conservative therapy group （n= 15）. We quantitatively measured the movement of the infarct segments with PWDTI one week, 1 month and 3 months after AMI. Results There were 382 abnormal wall motion segments in 72 patients. The peak systolic velocities （Vs）, systolic velocity-time integrals （VTIs）, acceleration of S wave（ACCs）and the ratio e to a （E/A） were all significantly higher in PCI group and thrombolysis group than in conservative therapy group at the 1 month and 3 months after AMI. There was no significant difference between PCI group and thrombolysis group. Conclusions PCI and thrombolysis treatment can significantly improve regional wall motion compared with conservative treatment.
出处
《中国心血管杂志》
2007年第3期172-174,共3页
Chinese Journal of Cardiovascular Medicine
基金
天津市高等学校科技发展基金(20020225)
关键词
急性心肌梗死
溶栓
经皮冠状动脉介入治疗
脉冲组织多普勒成像
局部室壁运动
Acute myocardial infarction
Thrombolysis
Percutaneous coronary intervention
Pulsed-wave Doppler tissue imaging
Regional wall motion
