摘要
目的:通过神经心理测试等手段,探讨慢性肾衰竭对患者认知状态的影响。方法:对39例40～60岁临床确诊为慢性肾衰竭的患者进行神经心理测试及人格和情绪状况测查,并对认知状态进行整体评定及分析。结果:慢性肾衰竭患者认知功能测验成绩均低于对照组,差异有显著性,并与人格的“精神质”和“情绪性”、健康自评等心理因素有关,“精神质”和“情绪性”越强,健康自评越差,认知障碍就越严重。慢性肾衰竭患者的焦虑和抑郁程度比对照组严重。结论:慢性肾衰竭患者存在着认知能力下降,且与躯体和心理因素有关,并且随着肾功能的恶化,这种表现更加明显。
Objective To examine the cognitive function of the chronic renal failure （CRF） patients and its correlation factors. Methods Thirty-nine CRF patients and 39 normal subjects with similar demographic characteristics were enrolled in the study. Neuropsychological test were performed and the personality and affective states were assessed for each patient, and then the relationship between cognitive function and creatinine, uria nitrogen, ferrohemoglobin or electrolure were analysed. Results The scores of cognitive tests in CRF patients were significantly lower than those in control subjects. The cognitive impairments were closely related to decreased blood perfusion in frontal and temporallobes. Patients with CRF were more depressive and anxious than control subjects, Conclusion Patients with CRF have some cognitive dysfunction, which is related to physical and psychological factors.
出处
《实用医学杂志》
CAS
2007年第11期1627-1629,共3页
The Journal of Practical Medicine
关键词
肾功能衰竭
慢性
认知
神经心理学测验
Kidney failure, chronic Cognition Neuropsychological tests
