摘要
目的观察炎琥宁冻干粉针剂治疗疱疹性咽颊炎的临床疗效。方法将90例疱疹性咽颊炎患者随机分为两组各45例,治疗组采用炎琥宁冻干粉针剂5～10 mg/(kg.d)加人5%葡萄糖注射液100 ml中静脉滴注,每天1次。对照组给予利巴韦林10～15 mg/(kg.d)加入5%葡萄糖注射液100 ml中静脉滴注,每天1次。结果总有效率治疗组95.56%,对照组88.89%,两组总有效率比较有显著性差异(P<0.05);两组平均住院时间及疱疹消失时间比较,有显著性差异(P<0.05),治疗组平均住院时间及疱疹消失时间明显短于对照组。结论炎琥宁治疗疹性咽颊炎具有良好抗病毒作用,无不良反应,疗程短,值得临床推广使用。
Objective To investigate the clinical effects of natrikalite dehydragrapholid succinas on herpangina. Methods 90 patients with herpangina were randomly assigned to receive natrikalite dehydrographolid succinas （5- 10 mg/kg/d ＋ 5 % GS 100ml, iv gtt qd） （n = 45 ） or ribavirin （ 10 - 15 mg/kg/d ＋ 5 % GS 100ml, iv gtt qd） （ control group, n = 45 ）. Results The total response rate in the treatment group and control group were 95.56% and 88.89%, respectively, the difference between two groups was significant （ P 〈 0.05 ）. The average hospital stay and disappearance time of herpes were significantly shortened in treatment group than that in control group （ P 〈 0.05 ）. Conclusion Natrikalite dehydragrapholid succinas has active antiviral effects, with no significant adverse reactions and quick onset of action. It＇s worthy of clinic application in the treatment of herpangina.
出处
《临床和实验医学杂志》
2007年第5期70-71,共2页
Journal of Clinical and Experimental Medicine
关键词
炎琥宁冻干粉针
疱疹性咽颊炎
Natrikalite dehydregrapholid succinas
Herpangina
