摘要
采用肝动脉化疗栓塞（TAE）结合B超引导下无水酒精注射（PEI），治疗23例不能手术切除，直径＞3cm的原发性肝癌病人。TAE＋PEI组疗效优于单纯TAE治疗组。TAE＋PEI组1，2，3年累计生存率分别为100％，84．0％和70．0％，而TAE组1，2，3年累计生存率则为68．2％，42．9％和21．5％，两组间累计生存率有非常显著性差异（P＜0．01）。TAE＋PEI组治疗后手术标本和细针穿刺组织病理检查显示，大多数病人肿瘤组织完全坏死。提示TAE＋PEI是不能手术切除的HCC较佳的治疗方法。
A combination of transcatheter arterial embolization(TAE) and percutaneous ethanol injection (PEI) was applied to 23 patients with hepatocellular carcinoma of more than 3cm in diameter and surgically unresectable. A group of liver cancer cases was treated solely by transcatheter arterial embolization as control. The results showed that after treatment,the decline in serum AFP level and reduction in tumor dia meter were significantly decline in serum AFP level and reduction in tumor diameter were significantly greater in the TAE+PEI group than those in the TAE group.The 1, 2 and 3-year survival rates of the TAE+PEI group were 100%, 84. 0% and 70. 0%,while those of the TAE group were 68. 2%, 42. 9 %. and 21. 5 % respectively.There was significant difference between the two groups in survival(P<0. 01). The results also revealed that the lesion was completely necrotic in most cases of the TAE+PEI group. The authors conclude that a combination of TAE and PEI is an appropriate treatment for patients with unresectable hepatocellular carcinoma.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1997年第1期32-35,共4页
Chinese Journal of Clinical Oncology
关键词
肝肿瘤
肝动脉栓塞疗法
药物疗法
PEI
B超引导
Hepatocelluar carcinoma Percutaneous ethanol injection Transcatheter arterial embolization
