摘要
生物芯片图像分析是生物芯片中至关重要的一个环节,图像分析效果的好坏直接影响到检测结果的精度和准确性,进而影响生物芯片的推广与使用。结合生物芯片图象的特点,对生物芯片图象去噪和样点自动识别作一综述。
Microarray imaging is consideredas an important tool for large scale analysis of gene expression. The accuracy of the gene expression depends on the experiment itself and further image processing. It＇s well known that the image analysis introduced during the experiment will greatly affect the accuracy of the gene expression. Microarray image analysis plays a potentially-arge impact on the gene detecting subsequent analysis （image segmentation,spot intensity and spot intensity extraction）.ln this paper, based on the characters of microarray images, the methods of microarray images＇ denoising and automatic-identification of the spot are reviewed.
出处
《中国医疗器械杂志》
CAS
2007年第2期108-111,共4页
Chinese Journal of Medical Instrumentation
基金
"十五"国家科技攻关计划项目"重大人兽共患病诊断平台"(2004BA519A46)
国家自然科学基金重点项目(39889001)资助。
关键词
生物芯片
图象去噪
样点自动识别
DNA microarray （biochip）, image denoising, automatic-identification of the spot
