摘要
目的:选择合适的地高辛片的分劈方法。方法:分别选择刀片分劈、剪刀分劈、双手对掰3种方法对地高辛片进行对半分劈,对各组的分劈片重量及损耗量差异进行分析,并采用USP剂量单位一致性测定方法对分劈片重进行测试,并对各分劈方法的适应性进行考察。结果:3种分劈片平均重量之间差异无显著性(P>0.05),剪刀分劈法导致的损耗量较大,3种分劈片重量均未通过USP剂量单位一致性测定,双手对掰法的适应性较好。结论:3种方法中,双手对掰法更适合于地高辛片的分劈。
Objective:To select the suitable method for splitting digoxin tablets.Methods:Three splitting methods which were knife splitting,forfex splitting and hands splitting were respectively applied to break digoxin tablets of three groups into halves.The fragment weight's variation of three groups was analysed and the level of fragment's weight uniformity of each group was determined by USP criteria.Each method's adaptability was investigated.Results:There was no significant difference between mean weight of each group and the others(P〉0.05).The loss weight of forfex splitting was larger.None of the three splitting methods was passed by USP criteria.The adaptability of hands splitting was better than the others.Conclusion:The hands splitting was more suitable for splitting digoxin tablets than using knife and forfex.
出处
《现代医药卫生》
2007年第9期1277-1278,共2页
Journal of Modern Medicine & Health
关键词
地高辛片
分劈
重量差异
损耗量
比较
Digoxin tablet
Splitting
Weight variation
Weight of loss
Comparison