3Hagen N A,Babul N.Comparative clinical efficacy and safety of a novel controlled-release oxycodone formulation and controlled-release hydromorphone in the treatment of cancer pain[J].Cancer,1997,79 (7):1428-1437.
4Heiskanen T,Kalso E.Controlled-release oxycodone and morphine in cancer related pain[J].Pain,1997,73 (1):37-45.
5Bruera E,Belzile M,Pituskin E,et al.Randomized,doubleblind,cross-over trial comparing safety and efficacy of oral controlled-release oxycodone with controlled-release morphine in patients with cancer pain[J].J Clin Oncol,1998,16(10):3222-3229.
6Mandema J W,Kaiko R F,Oshlack B,et al.Characterization and validation of a pharmacokinetic model for controlled-release oxycodone[J].Br J Clin Pharmacol,1996,42(6):747-756.
8Kaplan R,Parris W C,Citron M L,et al.Comparison of controlled-release and immediate-release oxycodone tables in patients with cancer pain[J].Clin Oncol,1998,16 (10):3230-3237.
9Salzman R T,Roberts M S,Wild J,et al.Can a controlled-release oral dose form of oxycodone be used as readily as an immediate-release form for the purpose of titrating to stable pain control?[J].J Pain Symptom Manage,1999,18 (4):271-279.
10Czarnecki M L,Jandrisevits M D,Theiler S C,et al.Controlled-release oxycodone for the management of pediatric postoperative pain[J].J Pain Symptom Manage,2004,27(4):379-386.
5Porter J, Jiek H. Addiction rare in patients treated with narcotics[J]. N Engl J Med 1980,302:123.
6Perry S, Heidrich G. Management of pain during debridement:a survey of U.S. burn units[J]. Pain 1982,13:267-280.
7Bloomfield SS , Cissell GB , Mitchell J, et al. Analgesic efficacy and potency of two oral controlled release morphine preparation[J].Clin pharmacol ther, 1993,53(4): 496.
5Wacnik P W,Eikmeier L J,Ruggles T R,et al.Functional interactions between tumor and peripheral nerve:morphology,algogen identification,and behavioral characterization of a new murine model of cancer pain[J].J Neurosci,2001,21(23):9355-9366.
6王庆华．恶性肿瘤化疗方案规范[M]．沈阳：辽宁科学技术出版社，2002：16．
7何青松.无痛人工流产麻醉临床分析[J].麻醉与镇痛,2011,18(27):68-69.
8Davies NM,,Reynolds J K,Undeberg MR,et al.Minimi-zing risks of NSAIDs:cardiovascular,gastrointestinal andrenal. Expert Review of Neurotherapeutics . 2006
9Sneader W.The discovery of aspirin: a reappraisal. British Medical Journal . 2000
10D Henry,P McGettigan.Epidemiology overview of gastrointestinal and renal toxicity of NSAIDs. International Journal of Clinical Practice . 2003
