摘要
目的探讨正常孕妇、妊娠期高血压病患者血浆D-二聚体水平及其检测意义。方法采用免疫比浊法分别测定20例正常非孕育龄妇女、60例正常孕妇(早、中、晚孕各20例)、30例妊娠期高血压病患者的血浆D-二聚体含量,分别比较各组间的差异。结果D-二聚体水平随孕周上升而增高,与对照组比较有统计意义(P<0.01);正常孕妇、妊娠期高血压病患者血浆D-二聚体水平明显增高,与对照组比较有统计意义(P<0.01)。结论正常孕妇处于相对高凝及继发性纤溶性增强状态,妊娠期高血压病患者更倾向于血栓形成和DIC发生。因此,产前检测血浆D-二聚体含量对病情监测和治疗有重要意义。
Objective To measure the D-dimer concentration and to explore the value of D-Dimer testing both in the healthy pregnant women and in the patients with hypertensive disorder complicating pregnancy. Methods Immunoturbidimetry was used in D-Dimer testing on twenty healthy unpregnant women ,sixty healthy pregnant women divided into three groups according as gestational weeks,thirty women with hypertensive disorder complicating pregnancy respectively.We also compare the difference of each groups and then evaluate its efficacy. Results D-Dimer was increased with each trimester. The healthy pregnant women and the women with hypertensive disorder complicating pregnancy had remarkably higher D-dimer concentrations than those of control group （P〈0.01）. Conclusion Normal pregnancy causes a progressive increase in circulating D- dimer. The hypertensive disorder complicating pregnancy has a high risk of diffuse intravascular clotting （DIC） occurrence .D- Dimer measurements in the antepartum have an important significance in monitoring and treatment of DIC.
出处
《中国现代医药杂志》
2007年第3期13-14,共2页
Modern Medicine Journal of China
