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急性心肌梗死患者纤维蛋白原含量与冠状动脉病变程度及预后有关 被引量:2

Fibrinogen is associated with severity of coronary artery disease and prognosis in acute myocardial infarction
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摘要 目的探讨纤维蛋白原(FIB)含量与急性心肌梗死(AMI)冠脉病变程度及预后的关系。方法根据AMI初期FIB含量将90例AMI分为两组,A组FIB值>4 g/L,B组FIB值≤4 g/L。将两组冠脉造影结果及预后进行比较分析。结果A组多支血管病变33例(占73%)、梗死相关血管近端病变36例(占80%)、心力衰竭10例(占22%)、严重心律失常14例(占31%)、梗死后心绞痛11例(占24%),与B组分项比较差异显著(P<0.05)。结论FIB增多的急性AMI多为多支血管病变,梗死相关血管多为近端病变,预后不好。 AIM To explore the relation between the severity of coronary artery disease, prognosis and fibrinogen in acute myocardial infarction (AMI). METHODS Ninety patients with AMI were divided into two groups (group A: fibrinogen 〉4 g/L, group B: fibrinogen-..〈4 g/L) based on fibrinogen. The data of both groups were compared with coronary angiographic findings and prognosis. RESULTS In group A, there were 33 (73%) muhivessel disease, 36 (80%) proximal lesions of infarction related artery, 10 (22%) cases of heart failure, 14 (31%) cases of serious cardiac arrhythmia, and 11 (24%) cases of post-infarction angina pectoris. There was significant difference in above indexes between group A and group B ( P 〈 0.05). CONCLUSION Muhivessel disease, proximal lesion of infarction related artery and poor prognosis are found in patients with AMI with high fibrinogen.
出处 《心脏杂志》 CAS 2007年第1期65-66,共2页 Chinese Heart Journal
关键词 心肌梗塞 急性 纤维蛋白原 冠状动脉疾病 myocardial infarction, acute fibrinogen coronary disease
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