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离子交换树脂度米芬复合物制备工艺优化

Optimization of Preparation Formulation of Compound of Ion-exchange Resins-Domiphen
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摘要 目的:制备苯乙烯系强酸型阳离子交换树脂度米芬复合物,并测定度米芬最大吸附量。方法:均匀设计优化度米芬树脂复合物的制备工艺,紫外分光光度法测定度米芬含量。结果:温度为55℃、药物树脂质量比为9:10、搅拌速度为500 r·min^(-1)、搅拌时间为2h为优化条件。结论:该优化工艺制备简单,成本低,效果好。 Objective: To study the preparation of compound of Ion-exchange resins-Domiphen and the measure of max attach to resin. Method: The praparation process was optimized by uniform design. The content of domiphen was determinated by ultraciolet spectrophotometry. Result: The conditions of optimization process were as followes:temperature was 55 ℃ ,mix blend time was 2 h, the ratio of medicine to resin was 9:10 and mix blend the speed was 500 r.min^-1. Conchlsion: The process is simple, the efficacy is good and costs is lowness.
作者 陈亮 童旭
出处 《中国药师》 CAS 2007年第3期261-262,共2页 China Pharmacist
关键词 离子交换树脂 度米芬 均匀设计 Ion exchange resins Domiphen Uniform design
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  • 1贵州省卫生厅.贵州省药品标准[M]贵州:贵州科技出版社,1992:297.
  • 2安登魁药物分析[M].第3版.北京:人民卫生出版社,1998:160.

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