摘要
目的检查分析15例新生儿Rh溶血病及发生原因,预防新生儿Rh溶血病的发生。方法采用盐水法检测患儿和其父母Rh血型,用新生儿溶血病血型血清学检查检测新生儿Rh溶血病,用Rh抗原谱细胞鉴定孕妇血清、患儿血清和红细胞抗体放散液中的Rh系统抗体。结果15例Rh溶血病患儿中由抗D引起的溶血病有8例,由抗D和Rh其他系统抗体联合引起的有2例,共10例,占66.7%;由抗E引起的有3例,由抗E和抗c联合引起的1例,占26.7%;由抗C引起的1例,占6.7%。15例患儿母亲都曾有生产或流产或输血史。结论为预防新生儿Rh溶血病的发生,对产前尤其是对曾有过生产史、流产史或输血史的孕妇作产前夫妇Rh血型和孕妇Rh免疫性抗体筛查极有必要。
Objective： To detecte and analyze 15 patients with Rh hemolytic disease and reason of invasion. To prevent beforehand Rh hemolytic disease. Methods： Rh blood group of patients with hemolytic disease and their parents were detected with saline - water test. Rh hemolytic disease of the newborn were detected with Rh hemolytic disease of the newborn blood group serologic examination. Rh system antibody in pregnancy serum and patients serum and irradiation liquid were detected with Rh spectrotype cell. Results： Of the 15 patients with Rh hemolytic disease, 8 patients were provoked by anti - D and 2 patients were by anti - D and other Rh system antibody, occupying 66. 7%. 3 patients were provoked by anti - E and 1 patient were provoked by anti - E and anti - c, occupying 26, 7%. 1 patient were provoked by anti - C, occupying 6. 7%. And 15 patients＇ mothers had already hayed childbearing or miscarriage or blood transfusion. Conclusion ： To prevent beforehand Rh hemolytic disease of the newbron, It is essential that Rh blood group of the couple are detected and gravidaR.h system antibody are screened before gravida＇childbearing especially before gravida＇childbearing who had already hayed childbearing or miscarriage or blood transfusion.
出处
《中国优生与遗传杂志》
2007年第3期68-69,共2页
Chinese Journal of Birth Health & Heredity
关键词
新生儿RH溶血病
RH血型
Rh系统抗体
Rh hemolytic disease of the newbron
Rh blood group
Rh system antibody
