摘要
目的探讨恶性胸膜间皮瘤的诊断和治疗方法。方法回顾分析我院1999.03—2006.03经病理确诊的18例恶性胸膜间质瘤患者的临床资料。结果本组18例中，男11例，女7例，男女之比为1．6：1。年龄以35。65岁多见。主要症状：胸痛15例，呼吸困难12例，咳嗽9例。15例胸部X线表现为大量胸腔积液，其中11例伴胸膜广泛增厚；13例胸腔穿刺抽液检查，其中8例血性胸液，5例为黄色胸液。11例外科手术活检确诊，7例胸腔穿刺取得病理。15例外科手术治疗，其中行根治术9例，术后2年生存率44．4％（4／9），5年生存率22．2％（2／9）；行姑息术6例，术后2年生存率16．7％（1／6），5年生存率为0。单纯化疗2例，2年生存率为0；未经治疗1例。1年内死亡。结论恶性胸膜间皮瘤以胸痛，呼吸困难，咳嗽为主要症状；以手术活检和穿刺活检为主要诊断方法；以手术为主要治疗方法，配合术后化疗效果更佳。
Objeetive To investigate the diagnosis and treatment of malignant pleural mesothehoma（MPM）.Methods The clinical data of 18 cases with MPM covering a period frome 1999 to 2006 were analyzed retrospectively.Results Of all the 18 cases, 11 cases are male,7 cases are female,male：female = 1.6：1 ,patients age.The main symptoms were chest pain（15/18） ,dyspnea（12/18）,cough（9/18）;Through the radiologic findings, we could find 15 cases showing plenty of pleural effusion and with pleural thickening among 10 of them;In the 13 analysis of pleural effusion cases,8 cases were blood- red,and 5 were yellow; 11 cases were diagnosed through the operation examination,7 cases were diagnosed via the needle biopsy of pleura;Among all the cases,15 patients were treated by surgical treatment,9 cases chose radical resection which the overall survival rates were 44.4% at 2 years and 22.2% at 5 years;6 cases chose palliative pleureetomy which the overall survival rotes were 16.7% at 2 years and 0% at 5 years;2 eases only chose chemotherapy which the overall survival rates were 0 % at 2 yeras; 1 case died within one year without any treatment. Conclusion Chest pain, dyspnea, cough are always showed on malignant pleural mesothelioma eases, the operation examination and needle biopsy of pleura are most important diagnosis measures;Surgical treatment is appropriate treatment for MPM, and the resuh of making the chemotherapy after surgical treatment is better.
出处
《黑龙江医学》
2007年第2期95-97,共3页
Heilongjiang Medical Journal
关键词
恶性胸膜间皮瘤
诊断
治疗
Malignant pleural mesothelioma
Diagnosis
Treatment
