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β-受体阻滞剂治疗心力衰竭的疗效观察 被引量:8

Therapeutic effect of β-blocker for patients with congestive heart failure
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摘要 目的:观察β-受体阻滞剂治疗充血性心力衰竭(CHF)的临床疗效。方法:将94例CHF患者随机分为β-受体阻滞剂组和常规治疗组,β-受体阻滞剂组在常规抗心衰治疗的基础上给予β-受体阻滞剂;常规治疗组采用安慰剂加常规抗心衰治疗。结果:β-受体阻滞剂治疗5年后再住院率和病死率,心功能及超声指标与常规治疗组相比均明显改善。结论:β-受体阻滞剂可显著改善CHF患者的远期预后。 Objective To investigate the therapeutic effect of β - blocker for the patients with congestive heart failure (CHF). Method 94 patients with CHF were randomly assigned to the β - blocker group ( n = 48) and the routine group ( n = 46). The β - blocker group was given β - blocker on the basis of anti - failure therapy, and the routine group was given placebo plus anti - failure therapy. Results After 5 years'treatment with β - blocker, a significant improvement was found in the rate of recurrent hospitalization and mortality, also cardiac function and echocardiography indicators compared with that of the routine group. Conclusion β - blocker can significantly improve the long - term prognosis of patients with CHF.
出处 《吉林医学》 CAS 2007年第1期62-63,共2页 Jilin Medical Journal
关键词 充血性 心力衰竭 Β-受体阻滞剂 Congestive heart failure β - blocker
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参考文献4

  • 1吴学思,李小鹰,许顶立,宁田海.全国世纪之交心力衰竭学术研讨会纪要[J].中华心血管病杂志,2002,30(1):2-6. 被引量:70
  • 2Heart Failure Society of America. HFSA guidelines for mannagement of patients with heart failure caused by left ventricularsystolic dysfunction - pharmacological approaches [ J ]. Pharmacotherapy, 2000,20:495.
  • 3Packer M. β - adrenergic blockade in chronic heart failure :principles, progress and practice [ J ]. Prog Cardiovasc Dis, 1998,41 ( 1Suppl 1 ) : 39.
  • 4Vittorio TJ, Lang CC, Katz SD, et al. Vasopressor responseto angiotensin Ⅱ infusion in patients with chronic heart failure receiving beta - blockers [ J ]. Circulation ,2003,107 (2) : 290.

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