摘要
目的：探讨宫腔内放置含左炔诺孕酮的T形宫内节育器（曼月乐）治疗子宫腺肌病的疗效。方法：选择46例患子宫腺肌病的已育妇女，选择月经周期第5—8天放置左炔诺孕酮T形宫内节育器。分别在放置前、放置后3个月、12个月观察其月经量、血红蛋白、痛经、子宫体积及血清中FSH、LH、E2水平的变化。结果：放置左炔诺孕酮T形宫内节育器后，患者的月经量较放置前明显减少（P〈0．01），18例患者出现时间长短不等的闭经；血红蛋白较放置前无明显增加（P〉0．05）；痛经明显减轻（P〈0．01）；子宫体积较放置前明显缩小（P〈0．05）；血清FSH、LH、E2水平较放置前无明显变化（P〉0．05）。结论：宫腔内放置左炔诺孕酮T形宫内节育器能明显减轻患者的临床症状，对卵巢功能无明显影响，能有效地提高患者的生活质量，有很好的临床应用价值。
Objective： To evaluate the effects and the side-effects of Mirena on treatment of adenomyosis. Methcds：Mirana were inserted into the 46 gravida cases with adenomyosis, on the 5 - 8th day of menstrual cycle.The menstrual blood loss, dysmenorrhoea scores, hemoglobin, uterine volume, and the levels of serum FSH, LH, E2 were recorded before insertion,threa months and 12 months after insertion respectively. Results.After insertion of Mirena, the menstrual blood loss significantly decreased （ P〈 0.01 ） ;Amenorrhoea occurred in 18 patients with different duration. But the level of Hemoglobin had no significantly increased （ P 〉 0.05）. The dysmenorrhoea scores became lower,evan vanished in some cases.The uterine volume decreased also （ P〈 0.05） .The serum FSH, LH,and E2 levels had no marked change （ P 〉 0.05）. Concluslons. Mirena inserting inside uterine cavity can significantly alleviate the clinical symptoms of adenomyosis with no effect on ovarian function. Moreover, it can improve the patients＇ living quality,and is quite promising in the clinical application.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2006年第12期742-744,共3页
Journal of Practical Obstetrics and Gynecology
关键词
子宫腺肌痛
左炔诺孕酮
宫内节育器
Adanomyosis Levonorgestrel（LNG）
Intrauterine contraceptive device（IUD）
